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Regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase

Authors: Tong Zhang, Raphaela Schwappacher, Shunhui Zhuang and Renate B Pilz

Citation: BMC Pharmacology 2009 9(Suppl 1):P79

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Published on: 11 August 2009

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Determination of new phosphorylation sites within natriuretic peptide receptors using mass spectrometric methods

Authors: Andrea R Yoder, Matthew D Stone, Tim Griffin and Lincoln R Potter

Citation: BMC Pharmacology 2009 9(Suppl 1):P75

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Published on: 11 August 2009

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Pharmacological characterization of receptor guanylyl cyclase reporter cell lines

Authors: Frank Wunder, Daniel Barufe, Annette Woermann and Markus Milde

Citation: BMC Pharmacology 2009 9(Suppl 1):P73

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Stimulation of soluble guanylate cyclase accelerates renal recovery following relief of unilateral ureteral obstruction

Authors: Yingrui Wang-Rosenke, Dmytro Khadzhynov, Tanja Loof, Stephanie Krämer, Bogdan Iliev, Alice Mika, Hans H Neumayer and Harm Peters

Citation: BMC Pharmacology 2009 9(Suppl 1):P71

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Published on: 11 August 2009

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Blockade of CNG channels abrogates urethral relaxation induced by soluble guanylate cyclase activation

Authors: Domingo Triguero, Maria Sancho, Marta García-Flores and Ángeles García-Pascual

Citation: BMC Pharmacology 2009 9(Suppl 1):P69

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Published on: 11 August 2009

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The role of cGMP-cGKI-signaling for duodenal bicarbonate secretion

Authors: Beate Spiessberger, Pascal Weinmeister, Franz Hofmann, Claudia Werner, Dieter Saur, Ursula Seidler, Wen Zheng, Jens Schlossmann and Robert Lukowski

Citation: BMC Pharmacology 2009 9(Suppl 1):P67

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Quantitation of cyclic dinucleotides by reversed-phase LC-MS/MS

Authors: Christian Spangler, Roland Seifert and Volkhard Kaever

Citation: BMC Pharmacology 2009 9(Suppl 1):P65

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Published on: 11 August 2009

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The degree of natriuretic peptide system activation in stable and high risk CHF characterized by increased cystatin C is not reflected in cGMP activation

Authors: John A Schirger, Horng H Chen, Josh Slusser, David Hodge, Denise Heublein, Alessandro Cataliotti, Sharon Sandberg and John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):P63

Content type: Poster presentation

Published on: 11 August 2009

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The neuronal PDE2A3 splice variant is targeted to membranes via dual acylation

Authors: Corina Russwurm, Georg Zoidl, Doris Koesling and Michael Russwurm

Citation: BMC Pharmacology 2009 9(Suppl 1):P61

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Published on: 11 August 2009

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Antihypertrophic actions of NO-independent soluble guanylyl cyclase (sGC) ligands BAY 41-2272 and BAY 58-2667 in vitro

Authors: Rebecca Ritchie, Jennifer Irvine, Jane Love, John Horowitz, Johannes-Peter Stasch and Barbara Kemp-Harper

Citation: BMC Pharmacology 2009 9(Suppl 1):P59

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Published on: 11 August 2009

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Nucleotidyl cyclase activity of recombinant soluble guanylyl cyclase

Authors: Kerstin Rauch, Johannes-Peter Stasch, Volkhard Kaever and Roland Seifert

Citation: BMC Pharmacology 2009 9(Suppl 1):P57

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Published on: 11 August 2009

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Synthesis and characterization of NS-2028 analogues

Authors: Anastasia Pyriochou, Athanasios Giannis and Andreas Papapetropoulos

Citation: BMC Pharmacology 2009 9(Suppl 1):P55

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Published on: 11 August 2009

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Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension

Authors: Joachim Mittendorf, Stefan Weigand, Cristina Alonso-Alija, Erwin Bischoff, Achim Feurer, Michael Gerisch, Armin Kern, Andreas Knorr, Dieter Lang, Klaus Muenter, Martin Radtke, Hartmut Schirok, Karl-Heinz Schlemmer, Elke Stahl, Alexander Straub, Frank Wunder…

Citation: BMC Pharmacology 2009 9(Suppl 1):P52

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Published on: 11 August 2009

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Thrombospondin-1 is a universal inhibitor of soluble guanylate cyclase activation

Authors: Thomas W Miller, Jeff S Isenberg and David D Roberts

Citation: BMC Pharmacology 2009 9(Suppl 1):P50

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Published on: 11 August 2009

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Negative feedback regulation within NO/cGMP pathway attenuates vasodilatory response in renovascular hypertension

Authors: Evanthia Mergia, Johannes Stegbauer, Sebastian Friedrich, Ivo Quack, Lars Christian Rump and Doris Koesling

Citation: BMC Pharmacology 2009 9(Suppl 1):P48

Content type: Poster presentation

Published on: 11 August 2009

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Quantification of cGMP in human plasma by isotope dilution LC-MS/MS

Authors: Jens Martens-Lobenhoffer, Christin Dautz and Stefanie M Bode-Böger

Citation: BMC Pharmacology 2009 9(Suppl 1):P46

Content type: Poster presentation

Published on: 11 August 2009

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Pro-B-Type natriuretic peptide: a novel, specific biomarker for detection of left ventricular dysfunction in the general community

Authors: Fima Macheret, Denise Heublein, Brian Lahr, Lisa Costello-Boerrigter, Guido Boerrigter, Paul McKie, Sharon Sandberg, Richard Rodeheffer, Alessandro Cataliotti and John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):P44

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Published on: 11 August 2009

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A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity

Authors: Yafelle Serulle, Ipe Ninan, Daniela Puzzo, Maria McCarthy, Latika Khatri, Ottavio Arancio and Edward Ziff

Citation: BMC Pharmacology 2009 9(Suppl 1):S44

Content type: Oral presentation

Published on: 11 August 2009

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Identification of novel target proteins of cGMP/cAMP signaling pathway using cGMP/cAMP capture compound mass spectrometry (CCMS)

Authors: Yan Luo, Olivia Baessler, Mirko Glinski, Michael Sefkow, Mathias Dreger and Hubert Koester

Citation: BMC Pharmacology 2009 9(Suppl 1):P42

Content type: Poster presentation

Published on: 11 August 2009

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Structural insights into sGC

Authors: Focco van den Akker, Xiaolei Ma, Faye Martin, Priyaranjan Pattanaik, Pius Padayatti, Matthew Warman and Annie Beuve

Citation: BMC Pharmacology 2009 9(Suppl 1):S42

Content type: Oral presentation

Published on: 11 August 2009

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cGMP kinase I regulates glucagon release

Authors: Veronika Leiss, Andreas Friebe, Franz Hofmann and Robert Lukowski

Citation: BMC Pharmacology 2009 9(Suppl 1):P40

Content type: Poster presentation

Published on: 11 August 2009

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Differential effects of selective PDE5 inhibitors in rat cerebral arteries in vitro and in vivo

Authors: Christina Kruuse, Saurabh Gupta, Elisabet Nilsson, Lars Kruse and Lars Edvinsson

Citation: BMC Pharmacology 2009 9(Suppl 1):P38

Content type: Poster presentation

Published on: 11 August 2009

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Structural and mechanistic insights into cGMP signaling

Authors: Annika Rauch, Michael Russwurm, Christine Schlicker, Martina Leipelt and Clemens Steegborn

Citation: BMC Pharmacology 2009 9(Suppl 1):S38

Content type: Oral presentation

Published on: 11 August 2009

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cGMP-dependent signaling pathways in spinal pain processing

Authors: Achim Schmidtko, Wei Gao, Peter König, Sandra Heine, Matthias Sausbier, Peter Ruth, Doris Koesling, Irmgard Tegeder, Andreas Friebe and Gerd Geisslinger

Citation: BMC Pharmacology 2009 9(Suppl 1):S37

Content type: Oral presentation

Published on: 11 August 2009

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BAY 58-2667, an NO-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts

Authors: Thomas Krieg, Yanping Liu, Thomas Rütz, Carmen Methner, Xi-Ming Yang, Stephan B Felix and James M Downey

Citation: BMC Pharmacology 2009 9(Suppl 1):P36

Content type: Poster presentation

Published on: 11 August 2009

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Progressive decline in circulating CNP with aging is associated with progressive cardiac fibrosis and myocardial impairment

Authors: Jeson Sangaralingham, Fernando L Martin, Paul M McKie, Tomoko Ichiki, Selma F Mohammed, Gerald E Harders, Elise A Oehler, Horng H Chen, Margaret M Redfield and John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):S35

Content type: Oral presentation

Published on: 11 August 2009

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The ANP/cGMP/cGMP-dependent protein kinase pathway counteracts Angiotensin II-stimulated calcium mobilization in cardiac myocytes

Authors: Michael Klaiber, Katharina Völker, Birgit Gaßner, Andrea Gerling, Susanne Feil, Robert Feil and Michaela Kuhn

Citation: BMC Pharmacology 2009 9(Suppl 1):P34

Content type: Poster presentation

Published on: 11 August 2009

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Cardiac natriuretic peptides inhibit TRPC6-mediated prohypertrophic signaling through cGMP-PKG pathway

Authors: Hideyuki Kinoshita, Koichiro Kuwahara, Ryuji Inoue, Motohiro Nishida, Hitoshi Kurose, Shigeki Kiyonaka, Yasuo Mori, Masaki Harada, Masao Murakami, Yasuaki Nakagawa, Shinji Yasuno, Satoru Usami, Masataka Fujiwara, Yoshihiro Kuwabara, Takeya Minami, Yuko Yamada…

Citation: BMC Pharmacology 2009 9(Suppl 1):P32

Content type: Poster presentation

Published on: 11 August 2009

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Cardio-renal protection of riociguat (BAY 63-2521) in low- and high-renin models of hypertension

Authors: Philipp Kalk, Yuliya Sharkovska, Bettina Lawrenz, Michael Godes, Linda Sarah Hoffmann, Kathrin Wellkisch, Sandra Geschka, Katharina Relle, Berthold Hocher and Johannes-Peter Stasch

Citation: BMC Pharmacology 2009 9(Suppl 1):P30

Content type: Poster presentation

Published on: 11 August 2009

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Regulation of soluble guanylyl cyclase by phosphorylation

Authors: Zongmin Zhou, Nazish Sayed, Anastasia Pyriochou, David Fulton, Annie Beuve and Andreas Papapetropoulos

Citation: BMC Pharmacology 2009 9(Suppl 1):S29

Content type: Oral presentation

Published on: 11 August 2009

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GAF domain-induced activation of phosphodiesterases 2 and 5

Authors: Ronald Jäger, Corina Russwurm, Doris Koesling and Michael Russwurm

Citation: BMC Pharmacology 2009 9(Suppl 1):P28

Content type: Poster presentation

Published on: 11 August 2009

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A molecular view of the regulation of sGC activity

Authors: Michael A Marletta, Emily R Derbyshire, W Kaya Erbil, Nathaniel B Fernhoff, John Kuriyan, Charles Olea Jr, Mark S Price and David E Wemmer

Citation: BMC Pharmacology 2009 9(Suppl 1):S27

Content type: Oral presentation

Published on: 11 August 2009

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Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation

Authors: Linda Sarah Hoffmann, Peter Michael Schmidt, Yvonne Keim, Stefan Schaefer, Harald Schmidt and Johannes-Peter Stasch

Citation: BMC Pharmacology 2009 9(Suppl 1):P26

Content type: Poster presentation

Published on: 11 August 2009

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Presynaptic cGMP-dependent protein kinase-I mediates synaptic potentiation in spinal amplification of pain

Authors: Ceng Luo and Rohini Kuner

Citation: BMC Pharmacology 2009 9(Suppl 1):S25

Content type: Oral presentation

Published on: 11 August 2009

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Lack of mechanical and thermal allodynia, and thermal hyperalgesia induced by peripheral neuropathic pain in NOS2 knockout mice

Authors: Arnau Hervera, Roger Negrete, Sergi Leánez and Olga Pol

Citation: BMC Pharmacology 2009 9(Suppl 1):P24

Content type: Poster presentation

Published on: 11 August 2009

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Role of cGMP-dependent protein kinases for fear memory formation in the lateral amygdala

Authors: Cindy Paul, Florian Schöberl, Pascal Weinmeister, Vincenzo Micale, Carsten Wotjak, Franz Hofmann and Thomas Kleppisch

Citation: BMC Pharmacology 2009 9(Suppl 1):S21

Content type: Oral presentation

Published on: 11 August 2009

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Forget cooperativity! – single-molecule signalling with cGMP

Authors: U Benjamin Kaupp

Citation: BMC Pharmacology 2009 9(Suppl 1):S19

Content type: Oral presentation

Published on: 11 August 2009

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Evaluation of ODQ as specific inhibitor of NO-sensitive guanylyl cyclase using mice deficient for the enzyme

Authors: Dieter Groneberg, Doris Koesling and Andreas Friebe

Citation: BMC Pharmacology 2009 9(Suppl 1):P18

Content type: Poster presentation

Published on: 11 August 2009

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GMP-mediated regulation of cardiovascular Ca²⁺ entry channel TRPC6 and its pathophysiological implications

Authors: Ryuji Inoue, Zhong Jian, Hai Lin, Shinichi Takahashi, Naomi Geshi, Akira Honda and Masayuki Mori

Citation: BMC Pharmacology 2009 9(Suppl 1):S17

Content type: Oral presentation

Published on: 11 August 2009

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Rescue of cGMP kinase I and the cause of premature death

Authors: Franz Hofmann, Robert Lukowski, Beate Spießberger, Jens Schlossmann and Pascal Weinmeister

Citation: BMC Pharmacology 2009 9(Suppl 1):S15

Content type: Oral presentation

Published on: 11 August 2009

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sGC activators and stimulators attenuate ischemia/reperfusion injury of the lung

Authors: Bakytbek Egemnazarov, Akylbek Sydykov, Ralph T Schermuly, Norbert Weissmann, Johannes-Peter Stasch, Werner Seeger, Friedrich Grimminger and Hossain A Ghofrani

Citation: BMC Pharmacology 2009 9(Suppl 1):P13

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Published on: 11 August 2009

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Acute heart failure syndromes

Authors: Mihai Gheorghiade

Citation: BMC Pharmacology 2009 9(Suppl 1):S13

Content type: Oral presentation

Published on: 11 August 2009

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Cardiovascular and gastrointestinal function of IRAG

Authors: Matthias Desch, Katja Sigl, Jörg Wegener, Robert Feil, Susi Feil, Franz Hofmann and Jens Schlossmann

Citation: BMC Pharmacology 2009 9(Suppl 1):P11

Content type: Poster presentation

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The role of cGMP and PKG in cardioprotection

Authors: James M Downey, Yanping Liu and Wenkwan Xin

Citation: BMC Pharmacology 2009 9(Suppl 1):S9

Content type: Oral presentation

Published on: 11 August 2009

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Mutation of three amino acids in the disulfide-ring of a CNP based chimeric natriuretic peptide alters its vascular properties

Authors: Horng H Chen, Brenda K Huntley, Alessandro Cataliotti, Fernando L Martin and John C Burnett Jr

Citation: BMC Pharmacology 2009 9(Suppl 1):P8

Content type: Poster presentation

Published on: 11 August 2009

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cGMP effects on vascular tone: modulating the activity of myosin light chain phosphatase

Authors: Frank V Brozovich

Citation: BMC Pharmacology 2009 9(Suppl 1):S7

Content type: Oral presentation

Published on: 11 August 2009

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The first crystal structure of cyclic GMP-dependent protein kinase Iβ dimerization/docking domain reveals molecular details of isoform-specific anchoring

Authors: Darren E Casteel, Eric V Smith-Nguyen, Banumathi Sankaran, Glen Spraggon, Eric N Hampton, Renate B Pilz, Susan S Taylor and Choel Kim

Citation: BMC Pharmacology 2009 9(Suppl 1):P6

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Published on: 11 August 2009

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Physiological roles of cGMP-gated channels: lessons from mouse models and human channelopathies

Authors: Martin Biel, Stylianos Michalakis, Xiangang Zong, Elvir Becirovic and Alexander Pfeifer

Citation: BMC Pharmacology 2009 9(Suppl 1):S5

Content type: Oral presentation

Published on: 11 August 2009

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Cyclic nucleotide phosphodiesterases – 40 years of progress

Authors: Joseph A Beavo, James Surapisitchat and Candance Parchen

Citation: BMC Pharmacology 2009 9(Suppl 1):S3

Content type: Oral presentation

Published on: 11 August 2009

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Manipulating the natriuretic peptide system for the treatment of pulmonary hypertension

Authors: Reshma S Baliga, Sarah Trinder, Chris J Scotton, Rachel C Chambers, Raymond J MacAllister and Adrian J Hobbs

Citation: BMC Pharmacology 2009 9(Suppl 1):P2

Content type: Poster presentation

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