Volume 11 Supplement 2

17th Scientific Symposium of the Austrian Pharmacological Society (APHAR)

Meeting abstracts

Innsbruck, Austria29-30 September 2011

Page 1 of 2

The anti-addictive drug ibogaine modulates voltage-gated ion channels and may trigger cardiac arrhythmias

Authors: Michael Kovar, Xaver Koenig, Ágnes Mike, René Cervenka, Péter Lukács, Hannes Todt, Walter Sandtner and Karlheinz Hilber

Citation: BMC Pharmacology 2011 11(Suppl 2):A1

Content type: Meeting abstract

Published on: 5 September 2011
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Neuropeptide Y Y₂ receptors modulate trace fear conditioning and spatial memory in the dorsal hippocampus

Authors: Ramon O Tasan, Dilip Verma, Mario Mietzsch, Stefan Weger, Regine Heilbronn, Herbert Herzog and Günther Sperk

Citation: BMC Pharmacology 2011 11(Suppl 2):A2

Content type: Meeting abstract

Published on: 5 September 2011
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Reduced fear conditioning after viral vector mediated neuropeptide Y administration into the basolateral amygdala

Authors: Dilip Verma, Ramon O Tasan, Mario Mietzsch, Stefan Weger, Regine Heilbronn, Herbert Herzog and Günther Sperk

Citation: BMC Pharmacology 2011 11(Suppl 2):A3

Content type: Meeting abstract

Published on: 5 September 2011
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Efficacy of systemic HS-198, an analogue of oxymorphone, on cancer pain-related behaviour in mice

Authors: Muhammad F Asim, Catalina R Bohotin, Cristina E Constantin, Helmut Schmidhammer, Michaela Kress and Mariana Spetea

Citation: BMC Pharmacology 2011 11(Suppl 2):A4

Content type: Meeting abstract

Published on: 5 September 2011
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Biological, pharmacological and immunological activities of novel 6-amino-acid-substituted 14-alkoxy-N-methylmorphinans

Authors: Elena Guerrieri, Valeria Follia, Dorota Garczarczyk, Silvia B Rief, Monika Fink, Muhammad F Asim, Mariana Spetea and Helmut Schmidhammer

Citation: BMC Pharmacology 2011 11(Suppl 2):A5

Content type: Meeting abstract

Published on: 5 September 2011
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Treprostinil stimulates the engraftment of haematopoetic stem cells

Authors: Filza Hussain, Christian Bergmayr, Armam Alimohammadi, Michael Freissmuth and Eva-Maria Zebedin

Citation: BMC Pharmacology 2011 11(Suppl 2):A6

Content type: Meeting abstract

Published on: 5 September 2011
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PI3Kδ is indispensable for CTL-mediated cytotoxicity

Authors: Eva M Putz, Michaela Prchal, Olivia Simma, Florian Forster, Xaver Koenig, Roland Piekorz, Michael Freissmuth, Veronika Sexl and Eva-Maria Zebedin

Citation: BMC Pharmacology 2011 11(Suppl 2):A7

Content type: Meeting abstract

Published on: 5 September 2011
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Pharmacoepidemiological aspects of outpatient pain medication

Authors: Eva-Maria Zebedin, Barbara Zikulnig, Thomas Burkhart and Anna Bucsics

Citation: BMC Pharmacology 2011 11(Suppl 2):A8

Content type: Meeting abstract

Published on: 5 September 2011
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Morphological characterization of large intercalated neurons provides novel insight on intrinsic networks of the amygdala

Authors: Daniela Busti, Thomas Bienvenu, Ben Micklem, Peter J Magill, Ryuichi Shigemoto, Marco Capogna and Francesco Ferraguti

Citation: BMC Pharmacology 2011 11(Suppl 2):A9

Content type: Meeting abstract

Published on: 5 September 2011
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Activation of kappa opioid receptors reduces EEG seizure activity in a mouse model of temporal lobe epilepsy

Authors: Luca Zangrandi and Christoph Schwarzer

Citation: BMC Pharmacology 2011 11(Suppl 2):A10

Content type: Meeting abstract

Published on: 5 September 2011
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Structural determinants of Ca_V1.3 L-type calcium channel gating

Authors: Andreas Lieb, Anja Scharinger, Florian Hechenblaickner, Mathias Gebhart, Alexandra Koschak, Martina J Sinnegger-Brauns and Jörg Striessnig

Citation: BMC Pharmacology 2011 11(Suppl 2):A11

Content type: Meeting abstract

Published on: 5 September 2011
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Timothy mutation affects tightly sealing point of Ca_V1.2 activation gate

Authors: Katrin Depil, Stanislav Beyl, Anna Stary-Weinzinger, Annette Hohaus, Eugen Timin and Steffen Hering

Citation: BMC Pharmacology 2011 11(Suppl 2):A12

Content type: Meeting abstract

Published on: 5 September 2011
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Development of novel N-methyl and N-allyl-substituted oxazolomorphinans and their interaction with opioid receptors

Authors: Attila Sipos, Levente Girán, Sándor Berényi, Sándor Antus, Helmut Schmidhammer and Mariana Spetea

Citation: BMC Pharmacology 2011 11(Suppl 2):A13

Content type: Meeting abstract

Published on: 5 September 2011
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Bacterial peptidoglycan enhances sickness behaviour induced by bacterial lipopolysaccharide

Authors: Aitak Farzi, Evelin Painsipp and Peter Holzer

Citation: BMC Pharmacology 2011 11(Suppl 2):A14

Content type: Meeting abstract

Published on: 5 September 2011
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Identification of novel ligands interacting with kappa opioid receptors

Authors: Mariana Spetea, Muhammad F Asim, Ilona P Berzetei-Gurske, Gerhard Wolber and Helmut Schmidhammer

Citation: BMC Pharmacology 2011 11(Suppl 2):A15

Content type: Meeting abstract

Published on: 5 September 2011
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Circular plant peptides as templates for GPCR drug discovery?

Authors: Johannes Koehbach, Margaret O’Brien, Marion Miazzo, David J Craik, Michael Freissmuth and Christian W Gruber

Citation: BMC Pharmacology 2011 11(Suppl 2):A16

Content type: Meeting abstract

Published on: 5 September 2011
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Neurodegeneration and histochemical plasticity in the rat subiculum after kainic acid-induced epilepsy

Authors: Meinrad Drexel, Adrian P Preidt, Elke Kirchmair and Günther Sperk

Citation: BMC Pharmacology 2011 11(Suppl 2):A17

Content type: Meeting abstract

Published on: 5 September 2011
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Novel pyrazole inhibitors for discrimination between receptor-operated and store-operated Ca²⁺ entry

Authors: Hannes Schleifer, Regina Oppenrieder, Sonia Stürmer, Bernhard Doleschal, Michael Poteser, Toma N Glasnov, C Oliver Kappe and Klaus Groschner

Citation: BMC Pharmacology 2011 11(Suppl 2):A18

Content type: Meeting abstract

Published on: 5 September 2011
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Amphetamine actions rely on the availability of phosphatidylinositol-4,5-bisphosphate

Authors: Florian Buchmayer, Klaus Schicker, Gerald Stübiger, Peter J Hamilton, Petra Geier, Andreas Jurik, René Weissensteiner, Thomas Steinkellner, Heinrich J Matthies, Therese Montgomery, Marie-Therese Winkler, Jae-Won Yang, Marion Holy, Gerhard F Ecker, Aurelio Galli, Valery Bochkov…

Citation: BMC Pharmacology 2011 11(Suppl 2):A19

Content type: Meeting abstract

Published on: 5 September 2011
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Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter

Authors: Sonja Sucic, Carina Kern, Dragana Vidovic, Subhodeep Sarker, Oliver Kudlacek, Harald H Sitte and Michael Freissmuth

Citation: BMC Pharmacology 2011 11(Suppl 2):A20

Content type: Meeting abstract

Published on: 5 September 2011
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LRET-based intramolecular distance measurements in LeuT_Aa

Authors: Azmat Sohail, Peggy Stolt-Bergner, Gerhard F Ecker, Michael Freissmuth, Thomas Stockner, Harald H Sitte and Walter Sandtner

Citation: BMC Pharmacology 2011 11(Suppl 2):A21

Content type: Meeting abstract

Published on: 5 September 2011
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The transcription factor STAT5 drives mutation and imatinib resistance in chronic myeloid leukemia via ROS production

Authors: Eva Grundschober, Wolfgang Warsch and Veronika Sexl

Citation: BMC Pharmacology 2011 11(Suppl 2):A22

Content type: Meeting abstract

Published on: 5 September 2011
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Statins modulate the expression profile of ATP-binding cassette transporters in human neuroblastoma cells

Authors: Bihter Atil, Evelyn Sieczkowski and Martin Hohenegger

Citation: BMC Pharmacology 2011 11(Suppl 2):A23

Content type: Meeting abstract

Published on: 5 September 2011
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Interaction of V-type ATPase inhibitors and extracellular NAADP-triggered calcium release in skeletal muscle cells

Authors: Florian Hiess and Martin Hohenegger

Citation: BMC Pharmacology 2011 11(Suppl 2):A24

Content type: Meeting abstract

Published on: 5 September 2011
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Simvastatin targets the IL-6 signalling cascade in human melanoma cells

Authors: Christine Wasinger, Christoph Minichsdorfer and Martin Hohenegger

Citation: BMC Pharmacology 2011 11(Suppl 2):A25

Content type: Meeting abstract

Published on: 5 September 2011
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Introduction of a 6-cyano group in 14-oxygenated N-methylmorphinans influences in vitro and in vivo pharmacological activities

Authors: Valeria Follia, Mario D Aceto, Louis S Harris, Andrew Coop, Helmut Schmidhammer and Mariana Spetea

Citation: BMC Pharmacology 2011 11(Suppl 2):A26

Content type: Meeting abstract

Published on: 5 September 2011
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Expression and differential distribution of the shaker-related voltage-gated potassium channel family (K_V1.x) in human hippocampus and neocortex

Authors: Irmgard Leitner, Georg Wietzorrek, Maria Trieb, Josef Marksteiner and Hans-Günther Knaus

Citation: BMC Pharmacology 2011 11(Suppl 2):A27

Content type: Meeting abstract

Published on: 5 September 2011
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Current-clamp experiments on primary hippocampal neurons shed light on the role of L-type voltage-gated calcium channels in depolarization shifts

Authors: Helmut Kubista, Lena Rubi, Petra Geier, Michael Lagler and Stefan Boehm

Citation: BMC Pharmacology 2011 11(Suppl 2):A28

Content type: Meeting abstract

Published on: 5 September 2011
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Characterization of CPCA-induced action on isolated rat femoral artery

Authors: Miroslav Radenković, Radmila Stevanović, Milica Stojiljković, Mirko Topalović and Marko Stojanović

Citation: BMC Pharmacology 2011 11(Suppl 2):A29

Content type: Meeting abstract

Published on: 5 September 2011
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Differential modulation of rNa_V1.4 channel inactivated states by lidocaine and its charged analogue QX222

Authors: Péter Lukács, René Cervenka, Xaver Koenig, Ágnes Mike, Michael Kovar, Karlheinz Hilber and Hannes Todt

Citation: BMC Pharmacology 2011 11(Suppl 2):A30

Content type: Meeting abstract

Published on: 5 September 2011
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Characterising the interaction between the COPII component SEC24C and the human serotonin transporter

Authors: Florian Koban and Sonja Sucic

Citation: BMC Pharmacology 2011 11(Suppl 2):A31

Content type: Meeting abstract

Published on: 5 September 2011
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Uremic albumin blocks reverse cholesterol transfer: role of lysine modifications

Authors: Veronika Binder, Michael Holzer, Dalia El-Gamal, Sabine Dirnberger and Gunther Marsche

Citation: BMC Pharmacology 2011 11(Suppl 2):A32

Content type: Meeting abstract

Published on: 5 September 2011
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Screening for serine/threonine kinases phosphorylating Stat5

Authors: Angelika Berger, Andrea Hölbl, Wolfgang Warsch and Veronika Sexl

Citation: BMC Pharmacology 2011 11(Suppl 2):A33

Content type: Meeting abstract

Published on: 5 September 2011
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Urea induces intercellular adhesion molecule-1 expression

Authors: Dalia El-Gamal, Michael Holzer, Veronika Binder, Sabine Dirnberger, Ákos Heinemann and Gunther Marsche

Citation: BMC Pharmacology 2011 11(Suppl 2):A34

Content type: Meeting abstract

Published on: 5 September 2011
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Teaching therapy-oriented pharmacology within a medical curriculum

Authors: Georg Wietzorrek

Citation: BMC Pharmacology 2011 11(Suppl 2):A35

Content type: Meeting abstract

Published on: 5 September 2011
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ABC transporters of Fasciola hepatica as putative drug targets

Authors: Ali El-Kasaby, Thomas Stockner and Oliver Kudlacek

Citation: BMC Pharmacology 2011 11(Suppl 2):A36

Content type: Meeting abstract

Published on: 5 September 2011
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Autocrine signalling as cause of sensitized cAMP formation

Authors: Christian Nanoff, Qiong Yang and Edin Ibrišimović

Citation: BMC Pharmacology 2011 11(Suppl 2):A37

Content type: Meeting abstract

Published on: 5 September 2011
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Differential regulation of amphetamine-induced serotonergic and dopaminergic efflux by syntaxin 1A

Authors: Therese Montgomery, Sonja Sucic, Thomas Steinkellner, Michael Freissmuth and Harald Sitte

Citation: BMC Pharmacology 2011 11(Suppl 2):A38

Content type: Meeting abstract

Published on: 5 September 2011
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129S1/SvImJ mice display impaired contextual fear extinction, enhanced fear incubation and deficit extinction consolidation phenotypes: rescue via pharmacological and non-pharmacological treatments

Authors: Nigel Whittle, Markus Hauschild, Marguerite Camp, Andrew Holmes and Nicolas Singewald

Citation: BMC Pharmacology 2011 11(Suppl 2):A39

Content type: Meeting abstract

Published on: 5 September 2011
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Modulation of magnesium deficiency-induced anxiety and HPA axis dysregulation by therapeutic drug treatment

Authors: Simone B Sartori, Nigel Whittle, Alfred Hetzenauer and Nicolas Singewald

Citation: BMC Pharmacology 2011 11(Suppl 2):A40

Content type: Meeting abstract

Published on: 5 September 2011
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The folding interactome of GPCRs

Authors: Christian Bergmayr, Christian Nanoff, Oliver Kudlacek, Michael Freissmuth and Christian W Gruber

Citation: BMC Pharmacology 2011 11(Suppl 2):A41

Content type: Meeting abstract

Published on: 5 September 2011
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Fear learning induces structural and functional plasticity at GABAergic synapses in the basolateral amygdala

Authors: Yu Kasugai, Elisabeth Vogel, Markus Hauschild, Ramon O Tasan, Yvan Peterschmitt, Andreas Lüthi, Ryuichi Shigemoto, Werner Sieghart, Nicolas Singewald, Günther Sperk and Francesco Ferraguti

Citation: BMC Pharmacology 2011 11(Suppl 2):A42

Content type: Meeting abstract

Published on: 5 September 2011
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Septal urocortin 3 modulates stress-coping behaviour but not hypothalamic-pituitary-adrenal axis activity during forced swimming

Authors: Karl Ebner, Alesja Rjabokon and Nicolas Singewald

Citation: BMC Pharmacology 2011 11(Suppl 2):A43

Content type: Meeting abstract

Published on: 5 September 2011
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Identification of a new C-terminal splice variant of Ca_V1.3 L-type calcium channels with unique functional properties

Authors: Gabriella Juhasz-Vedres, Anja Scharinger, Mathias Gebhart, Perrine Busquet, Chiara Poggiani, Simone B Sartori, Martina J Sinnegger-Brauns, Alexandra Koschak and Jörg Striessnig

Citation: BMC Pharmacology 2011 11(Suppl 2):A44

Content type: Meeting abstract

Published on: 5 September 2011
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Effect of orally administered moxaverine on ocular haemodynamics

Authors: Stefan Palkovits, Michael Lasta, Doreen Schmidl, Agnes Boltz, Reinhard Told, Semira Kaya, Gerhard Garhöfer and Leopold Schmetterer

Citation: BMC Pharmacology 2011 11(Suppl 2):A45

Content type: Meeting abstract

Published on: 5 September 2011
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[¹¹C]Elacridar as a novel P-glycoprotein PET tracer, assessment of whole-body distribution and radiation dosimetry in humans

Authors: Martin Bauer, Markus Zeitlinger, Georg Dobrozemsky, Cécile Philippe, Markus Müller and Oliver Langer

Citation: BMC Pharmacology 2011 11(Suppl 2):A46

Content type: Meeting abstract

Published on: 5 September 2011
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Role of nitric oxide in optic nerve head blood flow regulation while experimental increase of ocular perfusion pressure

Authors: Reinhard Told, Doreen Schmidl, Michael Lasta, Agnes Boltz, Berthold Pemp, Semira Kaya, Gerhard Garhöfer, Gabriele Fuchsjäger-Mayrl and Leopold Schmetterer

Citation: BMC Pharmacology 2011 11(Suppl 2):A47

Content type: Meeting abstract

Published on: 5 September 2011
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Inhibition of breast cancer resistance protein at the murine blood-brain barrier by Ko143 studied with [¹¹C]tariquidar and PET

Authors: Thomas Wanek, Claudia Kuntner, Jens P Bankstahl, Marion Bankstahl, Johann Stanek, Michael Sauberer, Markus Müller, Wolfgang Löscher and Oliver Langer

Citation: BMC Pharmacology 2011 11(Suppl 2):A48

Content type: Meeting abstract

Published on: 5 September 2011
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Salermide down-regulates sirtuin proteins to induce human cancer cell apoptosis

Authors: Asha Leisser, Michael Wolzt and Angela Storka

Citation: BMC Pharmacology 2011 11(Suppl 2):A49

Content type: Meeting abstract

Published on: 5 September 2011
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Capsaicin-sensitive sensory nerves, TRPV1 receptors and tachykinins play important roles in mast cell tryptase-induced arthritis and hyperalgesia

Authors: Zsuzsanna Helyes, Éva Borbély, Katalin Sándor, Adrienn Markovics, Erika Pintér, János Szolcsányi, John P Quinn and Jason J McDougall

Citation: BMC Pharmacology 2011 11(Suppl 2):A50

Content type: Meeting abstract

Published on: 5 September 2011
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17th Scientific Symposium of the Austrian Pharmacological Society (APHAR)

Meeting abstracts

BMC Pharmacology