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| |
GSH (μ mol/gm tissue)
|
GSSG (μ mol/gm tissue)
|
Ratio
|
|---|
|
Control
|
32.12 ± 2.6
|
11.3 ± 0.71
|
0.84
|
|
CCl4 treated
|
16.7 ± 1.05
|
19.6 ± 1.11
|
-1.14
|
|
Natansnin treated
|
30.03 ± 2.4
|
11.5 ± 0.85
|
0.65
|
|
Natansnin (10 mg) + CCl4 treated
|
26.8 ± 1.7
|
14.7 ± 0.9
|
-0.16
|
|
Natansnin (20 mg) + CCl4 treated
|
28.1 ± 1.91
|
14.1 ± 0.81
|
-0.007
|
- Reduced and oxidized glutathione levels were measured in liver homogenate from control, CCl4 and natansnin (10 mg/kg, 20 mg/kg body weight) treated rats. Glutathione levels are expressed as μmoles per gram tissue. Ratio = GSH-2(GSSG)/GSSG.